LGBTQIA+ patients face emotional, psychological, cultural and biological challenges unique to their gender identification and lifestyle. These patients develop both common dermatoses and cutaneous concerns specific to their sexual orientation. This presentation will offer a review of current scholarly articles. The purpose of the review is to enhance the knowledge of dermatology caregivers of the special needs and concerns of patients of the LGBTQIA+ community. The ultimate goal of this presentation is to promote respectful interactions and cultural sensitivity with this underserved patient population.